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Another Study Shows Antacid Drugs Increase Fracture Risk

A new study from researchers in Canada shows that long-term use of proton pump inhibitors (PPIs) for acid reflux and other disorders increases the risk of osteoperosis related fractures. PPIs are a group of drugs that prevent the production of gastric acid in the stomach. Some of the more common brands include Nexium, Prilosec and Prevacid. They are some of the most widely used drugs in America. In fact, last year alone American's spent about $7 billion dollars on medicines that inhibit or eliminate stomach acid. But these drugs may do more harm than good.

This latest study seems to support at least two other large scale studies showing a direct link between the PPIs and the risk of bone fractures.

Researchers conducting the study used administrative claims data to identify patients over age 50 that had a fracture of the hip, spine or wrist between 1996 and 2004. The 15,792 cases they found were matched with 47,289 controls.

The results, published in the August issue of the Canadian Medical Association Journal identified that prolonged use of PPIs increased the risk of fracture. Researchers found that after five years of continued PPI use the risk of hip fracture increased by 62%. After seven years the risk of hip fracture nearly quadrupled and the risk of other fractures doubled when compared to the controls.

This study showed the longest period of time to see problems related to PPI use. In 2006 University of Pennsylvania researchers reported that the use of PPIs for one year was associated with a 44% increase in risk of hip fractures. A Danish study showed similar results when researchers analyzed 125,000 with fractures and found that using PPIs for one year, more than doubled the risk of fractures.

More testing is necessary to identify how PPIs increase fracture risk. Some researchers believe that the increased is because PPIs inhibit stomach acid making it difficult for the body to absorb calcium. This could lead to accelerated bone mineral loss and weaker bones.

To learn more about how PPIs work and what you can do to protect yourself from heartburn, acid reflux and ulcers without using these type of drugs check out this free report: https://www.naturecity.com/blog/another-study-shows-antacid-drugs-increase-fracture-risk/
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