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Arginine Silicate May Significantly Improve Mental Performance

Two recent studies suggest that taking an inositol-stabilized arginine silicate supplement may improve cognitive performance on tests of mental-flexibility, processing speed, and executive functioning.


Participants in the first study included 11 healthy young men who were given either 1,500 mg of inositol-stabilized arginine silicate or a placebo daily for 14 days. The supplementation period was followed by a seven-day washout period, after which the men underwent the opposite intervention.


At the conclusion of the study, the supplement was associated with a 28% faster performance, compared to baseline, on the Trail Making Test, which assesses cognitive processing speed and executive functioning, when compared with the placebo.


Participants in the second study included 16 healthy young men who were given either the same dose of the arginine silicate supplement or a placebo for three days. The supplementation period was followed by a seven-day washout period, after which the men underwent the opposite intervention.


At the conclusion of the study, the supplement group performed 33% better than the placebo group on the Trail Making Test and 35% better than they did at baseline.


Researchers from QPS-Miami Research Associates conducted the study. It was published on November 18, 2016, in the journal Nutrients.


In the body, arginine changes into nitric acid. It has been shown in previous studies to help with cardiovascular health and lower blood pressure. It can be found in gelatin, chocolate, carob, coconut, oats, whole wheat flour, soybeans, and wheat germ.

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