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Berberine and Probiotics May Help Support Healthy Post Meal Lipid Levels

Post meal lipidemia is characterized by prolonged and increased levels of lipids, such as cholesterol and triglycerides, following a meal. Post meal lipidemia can be harmful to cardiovascular health. A new study has found that supplementation with berberine and probiotics may help reduce post meal lipidemia.

Participants in the study included 365 adults with type 2 diabetes. They were assigned to 1 of 4 12-week interventions:

  1. 600 mg of berberine and 4 grams of probiotics;
  2. 600 mg of berberine plus placebo;
  3. 4 grams of probiotics plus placebo;
  4. Placebo

Lipid levels were measured 120 minutes after consumption of a standard carbohydrate meal. The measurements were taken at baseline, week 4, week 8, and week 12.

Participants in the berberine and probiotic group saw the greatest improvements in post meal total cholesterol and LDL cholesterol. The next best performing group was those taking berberine only. Participants in the probiotic only group had very little benefit.

The study was conducted by researchers from the Shanghai Jiao Tong University School of Medicine. It was published online ahead of print on December 20, 2021 in the journal Gut Microbes.

A previous study found that berberine may help support healthy cholesterol levels.

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