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Blood Orange Extract May Help Reduce Oxidative Stress and Inflammation

Blood oranges are very nutritious and contain vitamin C, fiber, and antioxidants. According to a recent study, blood orange extract may help reduce systemic oxidative stress and inflammation. 

The researchers recruited 60 adults between the ages of 45 and 60 for the study. They were given 100 mg of blood orange extract or a placebo daily for 8 weeks. Levels of antioxidants and pro-inflammatory biomarkers were measured at baseline, week 2, and week 8. The Short Form Health Survey and Menopause Rating Scale were used to evaluate wellbeing at baseline and at the end of the study period. 

Participants in the blood orange group experienced improvements in several markers related to glutathione, which is known as the “master” antioxidant.  These changes started after 2 weeks, and continued improvement was noted after 8 weeks compared to the placebo group. These changes indicate reduced levels of oxidative stress.  

In addition, those in the blood orange group also saw a 2.5% decrease in the pro-inflammatory marker TNF-a at the end of the study period. Levels of wellbeing increased in the blood orange extract group in the areas of physical and emotional wellbeing and in general health factors. 

e University of Catania. It was published online ahead of print on October 11, 2022 in the journal Nutrients. 

A previous study found that a probiotic-enriched diet may help reduce inflammation markers. 

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