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Certain Blood Pressure Lowing Medications May Help Reduce Memory Decline

High blood pressure is a risk factor for cognitive decline. Researchers believe this is because high blood pressure reduces blood flow to the brain. A new study has found that hypertensive medications that cross the blood-brain barrier may help reduce the risk of memory decline.

The researchers looked at data from 14 studies that included approximately 12,900 adults. The studies looked at the association between hypertensive medications that do and do not cross the blood-brain barrier and cognitive function.

Participants taking blood-barrier crossing hypertensives had better memory recall during 3 years of follow-up compared to those taking non-blood-barrier crossing hypertensives. The blood-brain barrier prevents toxins and most drugs from entering the brain while also allowing vital nutrients to enter the brain.

The study was conducted by researchers from the University of California, Irvine. It was published online ahead of print on June 21, 2021, in the journal Hypertension..

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