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Coffee May Improve Cardiovascular Disease Risk Factors

Postprandial hyperglycemia and endothelial dysfunction are both risk factors for cardiovascular disease. A recent study suggests that the polyphenols in coffee may help lower blood glucose levels after meal ingestion and increase flow mediated dilation in healthy men.


Participants in the study included 19 healthy men who were given a test meal with either a polyphenol-rich coffee drink — containing 255 mg of chlorogenic acids — or a placebo drink that contained no chlorogenic acids. Both the placebo and the polyphenol-rich drink contained 54.9 mg of caffeine.


The researchers measured blood biomarkers and flow mediated dilation after the participants ingested their meal and up to three hours after the meal. They found that the polyphenol-rich drink was associated with significantly lower increases in blood glucose and that flow mediated dilation increased.


Flow mediated dilation measures the ability of an artery to contract as blood flows through it and the higher your flow mediated dilation, the better. Previous research suggests that every 1% reduction in flow mediated dilation is associated with a 12% increased risk in developing cardiovascular problems.


Researchers from the Kao Corporation in Japan conducted the study. It was published online ahead of print on August 4, 2015, in Nutrition Research.


The health benefits associated with coffee are generally attributed to its polyphenol content. These benefits include reducing the risk of developing diabetes, prostate cancer, cirrhosis and oral cavities.


Previous studies have linked polyphenol intake with a variety of health benefits, including helping with weight management, fighting certain cancers, and reducing inflammation. Polyphenols can be found naturally in many foods, including honey, a variety of fruits and vegetables, red wine, chocolate, tea, certain oils and many types of grain.

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