Combination Supplement May Help Improve Cognitive Function
Ferulic acid is an antioxidant found in the cell walls of some plants. Angelica archangelica is a plant whose roots are used to make herbal medicines. A recent study has found that supplementation with ferulic acid and Angelica archangelica may help improve cognitive function.
Participants in the study included 47 adults with an average age of 75 who had been diagnosed with mild cognitive impairment. They were given 200 mg of ferulic acid and 40 mg of Angelica archangelica or a placebo daily for 48 weeks. Cognitive function was assessed at baseline, week 24, and week 48 using the Alzheimer Disease Assessment Scale (Japanese version) cognitive subscale (ADAS-Jcog) and the Mini-Mental State Exam (MMSE).
Participants in the supplement group saw significant improvements in their ADAS-Jcog scores at 24 and 48 weeks compared to the placebo group. Improvements were especially significant for word recall at week 24 and orientation at week 48. MMSE scores were significantly better in the supplement group at week 24 compared to the placebo group.
The study was conducted by researchers from Juntendo University. It was published on September 18, 2020 in the Journal of Alzheimer's Disease Reports.