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Curcumin Plus Piperine May Ease Osteoarthritis Suffering

Knee osteoarthritis is a painful illness that affects mobility.  It results from aging and wear and tear on the knee. A recent study suggests that curcumin and piperine may improve symptoms of knee osteoarthritis. 

Participants in the study included 40 people with mild to moderate knee osteoarthritis. Over the course of six weeks, 19 of them took 1500 mg of a combination of curcuminoids and piperine three times daily, while the other half took a placebo.

At the conclusion of the study, the curcumin/piperine group had improvements in osteoarthritis impairment as measured by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analogue scale, and Lequesne’s pain functional index. The curcumin group showed improvements in all of the tests, with the exception of the stiffness section of the WOMAC score.

Researchers from Baqiyatallah University of Medical Sciences in Tehran conducted the study. It was published online ahead of print on May 22, 2014, in Phytotherapy Research.

Curcumin has been used in folk remedies for years to ease menstrual cramping, help heal wounds, and to improve the appearance of skin. Recent studies have suggested that it may also protect against prostate cancer, Alzheimer’s, diabetes and arthritis. All of these benefits are attributed to the anti-inflammatory properties of curcumin.

The spiciness of black pepper is due to the alkaloid piperine, which has antioxidant and anti-inflammatory properties.  It has been used for centuries in traditional Eastern medicine to treat gastrointestinal distress, pain and inflammation.


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