Curcuminoids Plus Piperine May Help Improve Cholesterol in Diabetics
People with type 2 diabetes are at a higher risk of poor cholesterol levels and heart disease. A recent study suggests that taking a combination of curcuminoids and piperine from black pepper may improve cholesterol markers in people with diabetes.
Participants in the study included 118 people with type 2 diabetes. Over the course of 12 weeks, they were given either a supplement containing 1000 mg of curcuminoids plus 10 mg piperine or a placebo daily. Serum concentrations of total cholesterol, LDL cholesterol, HDL cholesterol, non-HDL-C and triglycerides were measured at baseline and at the end of the study.
At the conclusion of the study, the researchers noted a 22 mg/dL reduction in total cholesterol levels and a 23.4 mg/dL reduction in non-HDL cholesterol levels in the supplement group. In comparison, the placebo group had reductions of 17 mg/dL for both total cholesterol and non-HDL cholesterol. They also noted a 1.5 mg/dL reduction in lipoprotein A, compared with a 0.3 mg/dL in the placebo group. Finally, the supplement group had a 1.56 mg/dL increase in HDL cholesterol, compared to only 0.2 mg/dL in the placebo group.
Researchers from Baqiyatallah University of Medical Sciences in Iran led the study. It was published in the August 2017 issue of Complementary Therapies in Medicine