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Flavanone-Rich Grapefruit Juice Linked to Reduced Arterial Stiffness

A recent study suggests that flavanone-rich grapefruit juice may improve arterial function by reducing carotid-femoral pulse wave velocity. Carotid-femoral pulse wave velocity is considered the gold standard measurement of central arterial stiffness.


 Participants in the study included 48 healthy postmenopausal women who were given either 340 ml of grapefruit juice containing 210 mg of naringenin gllycosides or a control drink daily for six months. That was followed by a two-month washout period, after which the participants crossed over to the other intervention.


 After six months of supplementation, mean carotid-femoral pulse wave velocity in the grapefruit juice group was 7.36 m/s, compared to 7.70 m/s in the placebo group. That reduction was considered to be statistically significant.


 However, no changes were found in endothelial function, blood pressure, or markers of inflammation and oxidative stress.


 The researchers believe that the reduction in carotid-femoral pulse wave velocity seen in this study could correspond with a 5% reduction in the global CVD risk.


 Researchers from the French National Institute for Agricultural Research and the French National Institute for Health and Medical Research conducted the study. It was published online ahead of print on May 27, 2015, in The American Journal of Clinical Nutrition.


 Flavonones are naturally occurring antioxidants which have previously been shown to decrease inflammation, protect our DNA from damage, and improve heart and brain health by increasing blood flow.


 In addition to being packed with flavanones, grapefruits are rich in antioxidants and vitamin C. They have been shown to help ease arthritis symptoms, lower cholesterol and promote better digestion.


 


 

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