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Gamma-Aminobutyric Acid Supplementation Associated With Increased Muscle Mass | NatureCity


Muscle hypertrophy is a term for the growth and increase of the size of muscle cells. The most common type of muscular hypertrophy occurs as a result of physical exercise such as weightlifting. A recent study suggests that oral supplementation with gamma-aminobutyric acid (GABA) may enhance exercise-induced muscle hypertrophy.





Twenty-one resistance-trained men between the ages of 26 and 48 participated in the study. Half of them took 10 grams of whey protein and 100 mg of GABA daily for 12 weeks. The other half took 10 grams of whey protein only daily for 12 weeks. All participants performed the same resistance training twice per week. Muscle mass was measured at baseline and after 12 weeks using dual-energy X-ray absorptiometry. 





The GABA supplement group had significantly elevated levels of growth hormone serum levels at 4 and 8 weeks, compared to baseline. The whey only group didn’t have significantly elevated levels until week 8. After 12 weeks, the GABA group had significantly greater increase in muscle mass and whole body fat-free mass compared to the whey only group.





The study was conducted by researchers from Ritsumeikan University, Japan. It was published online ahead of print on May 11, 2019 in theJournal of Clinical Medicine Research.


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