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Glucosamine and Chondroitin May Lower Biomarker of Inflammation

Systemic inflammation is common in individuals who are overweight or obese and has been linked with higher risk of chronic disease. A recent study suggests that taking glucosamine hydrochloride and chondroitin sulfate may reduce levels of the inflammation biomarker C-reactive protein in overweight people.


Participants in the study included 18 otherwise healthy overweight men and women who were given either 1,500 mg of glucosamine hydrochloride and 1,200 mg chondroitin sulfate or a placebo daily for 28 days. At the conclusion of the study, the researchers found that the supplement group had a 23% reduction in C-reactive protein when compared with the placebo.


Researchers from the Fred Hutchinson Cancer Research Center in Seattle, Harvard School of Public Health, and Vanderbilt University conducted the study. It was published on February 26, 2015, in PLoS ONE.


Glucosamine is produced naturally in the body and helps with joint function. Glucosamine supplements have been found to help with osteoarthritis, reducing joint pain and improving joint function.


Chondroitin is found in and around the cells of cartilage, and provides cartilage with strength and resilience. Previous research has found that chondroitin may help ease the pain of arthritis and osteoporosis, lower cholesterol and possibly help with ulcerative colitis and Crohn’s disease.

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