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Hemodialysis Patients May Benefit From Vitamin K2 Supplementation

A recent study suggests that hemodialysis patients are particularly at risk of vitamin K2 deficiency and could benefit from taking vitamin K2 supplements.


Participants in the study included 50 hemodialysis patients who were given 360 µg of menaquinone-7 (vitamin K2) daily for four weeks. The researchers measured inactive vitamin K levels as well as vascular calcification at the beginning and end of the supplementation period.


The researchers found that hemodialysis patients have a 40% lower vitamin K2 intake than healthy individuals. This was determined by the high plasma levels of dp-ucMGP in the participants’ blood. Supplementation was associated with an 86% decrease in dp-ucMGP at the end of the four-week study period.


The researchers also found that high dp-ucMGP levels was significantly correlated with high vascular calcification. Vascular calcification is a common complication in hemodialysis patients and can lead to cardiovascular complications.


Researchers from PLACE conducted the study. It was published on June 7, 2017, in BMC Nephrology.


Previous studies have linked vitamin K2 to bone and cardiovascular health, as well as a reduced risk of prostate cancer. Vitamin K2 can be found in fermented foods such as cheese but can also be found in meat and soybeans. It is also available in supplement form.

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