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High Dose Folic Acid Supplementation May Help Support Blood Sugar Health

High Dose Folic Acid Supplementation May Help Support Blood Sugar Health

Folic acid is a synthetic version of the B vitamin folate. The body uses folate to make and repair DNA, help cells grow, divide, and work properly, and help red blood cells mature. A new study has found that supplementation with a high dose of folic acid may help support blood sugar health.

For their study, the researchers enrolled 100 adults with type 2 diabetes and an average age of 60. They received 5 mg of folic acid or a placebo daily for 12 weeks. The researchers evaluated fasting blood glucose, serum insulin, homocysteine levels, and sortilin serum levels. Homocysteine and sortilin serum levels are biomarkers correlated to insulin resistance.

Participants in the folic acid group saw an 8.7% decrease in fasting blood glucose, a 13.7% decrease in serum insulin, and a 21.7% decrease in insulin resistance. They also saw a 28.2% decrease in homocysteine levels and a 33.7% decrease in sortilin serum levels. No significant changes were seen in the placebo group.

The study was conducted by researchers from Kafrelsheikh University.  It was published online ahead of print on June 22, 2022 in the journal Nutrition & Diabetes.

Mulberry fruit was found to provide blood sugar health benefits in a previous study.

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