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High Omega-3 Index Associated With Lower Risk of Mortality

The Omega-3 Index is a measure of the amount of EPA and DHA in the blood, specifically the red blood cell membranes. A new study has found that having an Omega-3 Index 7.6% or higher may be associated with up to a 13% lower risk of all-cause mortality.

A group of over 50 fatty acids research scientists reviewed 17 cohort studies that evaluated the association between blood omega-3 levels and the risk for all-cause mortality. The studies were conducted in 10 different countries and included 42,266 participants. The shortest follow-up period was a little over 5 years, and the longest was a little more than 32 years.

Participants with the highest Omega-3 Index value (7.6%) were found to have a 13% lower risk of all-cause mortality compared to those with the lowest Omega-3 Index (3.5%). They were also found to have a 15% reduce risk of cardiovascular disease death and an 11% reduced risk of death from cancer.

The study was conducted by researchers from the Fatty Acids and Outcomes Research Consortium. It was published online ahead of print on April 22, 2021 in the journal Nature Communications.

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