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Hot Flashes Cooled Down By Daidzein

Researchers at the Harvard Medical School have found that the soy isoflavone daidzein was effective in reducing hot flashes in menopausal women by up to 52%.

The results of the study were published in the January 2008 edition of Menopause, the journal of the North American Menopause Society.

The researchers studied 147 menopausal women between the ages of 38 and 60 who experienced from 4 to 14 hot flashes per day.  The women were divided into different groups that either received daidzein or a placebo.  After 12 weeks, the women taking daidzein reported a reduction in hot flashes of 52% compared to a 39% reduction in the placebo group.

This lead researchers to conclude that daidzein supplementation may be an effective and acceptable alternative to hormone treatment for menopausal hot flashes.

An interesting result of this study is the high placebo effect as evidenced by the 39% reduction experienced by the placebo group.

This research is the latest in the ongoing debate in the scientific community over the efficacy of soy isoflavones on menopausal symptoms.


Menopause; January 2008, Volume 15, Issue 1, Pages 125-134; "Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women"; L. Khaodhiar, H. Ricciotti, L. Li, W. Pan, M. Schickel, J. Zhou, G. Blackburn.
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