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Hyaluronan May Increase Skin Moisture and Improve Facial Signs of Aging

Taking supplements of the high-viscosity macromolecular polymer hyaluronan (also known as hyaluronic acid) may increase skin moisture and improve luster and suppleness of the face in people with dry skin.

Participants in the study included 61 women aged 35 to 60 with dry skin. Over the course of six weeks they took either 120 mg of Hyaluronsan HA-F or Hyabest (S) LF-P or a placebo daily. Hyaluronsan HA-F has a molecular weight of 800k and Hyabest(S) LF-P has a molecular weight of 300k.

At the conclusion of the study, the researchers found that both hyaluronan groups showed improvements in skin moisture when compared with the placebo group. The group that took the Hyabest(S) LF-P showed the highest increases in skin moisture content, and the highest increase was recorded two weeks after the end of the ingestion period.

The participants filled out a questionnaire before ingestion began, after 3 and 6 weeks of ingestion, and 2 weeks after ingestion ended. Results of the questionnaires showed that subjective facial aging symptoms including luster, suppleness, and wrinkles were significantly improved in the HA groups when compared with the placebo.

The researchers noted no negative side effects on the skin in the HA groups.

Researchers from the Kewpie Corporation and Toho University Shashi Medical Center conducted the study. It was published online ahead of parting on November 1, 2014, in the Journal of Clinical Biochemistry and Nutrition.

Hyaluronan is found naturally throughout the body. Previous studies suggest that it may help provide relief for dry eyes and helps lubricate the joints, similar to the way that oil lubricates an engine.

Some foods that are good sources of hyaluronan are fish oil, vitamin C-rich fruits, and foods rich in magnesium such as broccoli, kale, avocados and carrots. You can also take a high quality supplement to increase your hyaluronan intake.

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