Link Found Between Vitamin D and Reducing Prostate Cancer Risk
It is believed that chronic prostate inflammation may lead to the development of prostate cancer. A recent study has found that vitamin D may increase expression of a gene that reduces inflammation in the prostate.
For this study, researchers tracked the gene GDF-15, which is highly expressed in the prostate and has been associated with inflammation. No difference was found in levels of GDF-15 in normal tissue and prostate cancer tissue. However, when prostate tissue with inflammation was examined, the researchers discovered that levels of GDF-15 were significantly low.
This study was the first to use a new and sophisticated algorithm to determine the expression of the GDF-15 gene and levels of inflammation. The researchers found that GDF-15 suppresses inflammation by inhibiting NFkB, which has been shown to promote inflammation as well as tumor formation and growth.
The researchers were also able to demonstrate that vitamin D upregulates the expression of GDF-15, which means it increases its activity level of inflammation suppression.
Researchers from the CU School of Medicine Department of Pathology conducted the study. It was published online ahead of print on October 18, 2014, in the journal The Prostate.
Previous studies have associated vitamin D with reducing the risk of skin damage, reducing the risk of osteoporosis, combating diabetes, and improving age related macular degeneration.
Vitamin D can be found in milk, fortified cereals, fish, and eggs. Your body also processes vitamin D from the sun but it becomes harder for our bodies to process it as we age. A high quality vitamin D supplement is always a good option if you feel that you’re not getting enough through diet and sun.