Non-Animal Derived Chondroitin Sulfate May Help Improve Knee Discomfort
Chondroitin sulfate is often used to help improve knee discomfort, however questions regarding the safety and purity of animal derived chondroitin sulfate have arisen. A new study evaluated the efficacy of chondroitin sulfate of non-animal origin and found that it may help improve knee function, pain, and inflammation markers.
Sixty adults over the age of 55 participated in the study. All of them were sedentary, overweight, and experiencing mobility impairment, joint discomfort, or had been diagnosed with knee osteoarthritis. The participants took 600 mg of non-animal derived chondroitin sulfate or a placebo daily for 12 weeks. The researchers assessed knee-pain, quality of life, related inflammation markers, and body composition at baseline and at weeks 4 and 12.
Participants in the supplement group saw significant decreases in their scores on the Western Ontario and McMaster Universities Osteoarthritis Index pain scale compared to placebo. They also saw improvements in the Tegner Lysholm Knee Scoring scale, which measures knee functions and symptoms. Levels of inflammations biomarkers decreased in the supplement group, and self-reporting of knee pain also decreased.
The study was conducted by researchers from the University of Pavia. It was published on August 29, 2019 in the journal Nutrients.