Omega-3 Linked WIth Cardio-Protective Benefits Against Air Pollution
Fine particulate matter (PM2.5) is an air pollutant, and long-term exposure may increase the risk of chronic bronchitis, reduce lung function, and worsen asthma and heart disease. A new study has found that omega-3 fatty acids may provide cardio-protective benefits against PM2.5.
included 65 healthy college students in Shanghai. Half of the group
received 2.5g of fish oil and half of the group received a placebo daily
for four months. The participants received four rounds of health
examinations during the last two months of the study. These
examinations measured blood pressure and 18 biomarkers of systematic inflammation, coagulation, endothelial functions, oxidative stress, antioxidant activity, and neuroendocrine stress. Fixed-site PM2.5 concentrations on campus were measured in real time.
The researchers used linear mixed-effect models to assess the effects of PM2.5 on the participants. They found that omega-3 supplementation had a beneficial effect on 5 biomarkers of blood inflammation, coagulation, endothelial function, oxidative stress, and neuroendocrine stress. In the placebo group, most of the biomarkers of cardiovascular health responded significantly and negatively PM2.5 fluctuations.
study was conducted by researchers from Fudan University, Shanghai and
the University of Michigan. It was published online ahead of print on
April 10, 2019 in the Journal of the American College of Cardiology