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Probiotic Strain May Ease Irritable Bowel Syndrome Symptoms

Irritable Bowel Syndrome (IBS) affects between 25 and 45 million people in the United States. A recent study suggests that taking supplements containing the probiotic Saccharomyces cerevisiae CNCM I-3856 may help improve gastrointestinal symptoms for people suffering from IBS.


Researchers examined data from two randomized clinical studies, which included 579 people with IBS. Both studies looked at the effects of Saccharomyces cerevisiae CNCM I-3856 on gastrointestinal symptoms in people with IBS. Changes in symptoms were measured using daily Likert scale scores of abdominal pain, scores of discomfort and bloating, and stool frequency and consistency.


After analyzing the data, the researchers found that the Saccharomyces cerevisiae CNCM I-3856 supplement was associated with a 12.3% decrease in pain/gastrointestinal discomfort when compared with the placebo. When they focused specifically on people suffering from constipation, they found that the supplement was associated with a 12.3% reduction when compared with the placebo. Finally, stool consistency in the Saccharomyces cerevisiae CNCM I-3856 group was significantly higher and classified as normal when compared with the placebo group.


Researchers from Lesaffre Group, Biofortis - Mérieux NutriSciences, Claude Huriez Hospital, Lille University North of France, and INSERM conducted the study. It was published online ahead of print on January 14, 2017, in World Journal of Gastroenterology.


Saccharomyces cerevisiae CNCM I-3856 has been shown in previous studies to improve symptoms of IBS and help with gastrointestinal distress. It can be found in baker’s yeast as well as in supplemental form.

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