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Probiotic Supplementation May Provide Blood Sugar Benefits

A previous study found that supplementation with magnesium may be beneficial to blood sugar health. Now a new study suggests that supplementation with three probiotic strains may provide blood sugar benefits.

The researchers recruited 56 participants with type 1 diabetes between the ages of 6 and 18 for their study. They were given 10 billion CFUs of the probiotic strains Lactobacillus salivarius subsp. salicinius AP-32, L. johnsonii MH-68, and Bifidobacterium animalis subsp. lactis CP-9 or a placebo daily for 6 months. All participants continued to receive regular insulin injection therapy.

The researchers measured fasting blood glucose levels and the amount of glucose in the blood at baseline, at the end of the study period, and 3 months after the end of the study period. They also measured pro-inflammatory markers and the bacterial composition of the e gut microbiota.

Participants in the probiotic group saw a decrease in fasting glucose levels from 185.4 mg/dl to 161.9 mg/dl, compared to no real change in the placebo group. They also saw a decrease in A1C levels, which is a measure of the average amount of glucose in the blood over 2 to 3 months, from 9.3% to 8.5%. These changes were still in evidence 3 months after the end of the study period. 

In addition, participants in the probiotic group saw an increase in beneficial bacteria in the gut microbiota and a significant reduction in pro-inflammatory markers.

The study was conducted by researchers from China Medical University. It was published online ahead of print on March 1, 2022 in the journal Frontiers in Endocrinology.

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