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Probiotics May Reduce Nausea and Vomiting During Pregnancy

During the first trimester of pregnancy, many women experience frequent bouts of nausea and vomiting. It usually starts around the 6th week of pregnancy, is at its worst around week 9, and stops by weeks 16 to 18. A new study suggests that supplementation with probiotics may help reduce nausea, vomiting, and constipation during pregnancy.

Participants in the study included 32 pregnant women. The study lasted 16 days. Participants went through 2 cycles that consisted of taking probiotics for 6 days and then not taking probiotics for 2 days. The probiotic supplement contained 10 probiotics including L. plantarum 299v, L. bulgaricus Lb-87, L. paracasei DSM 13434, L. plantarum DSM 15312, L. salivarius Ls-33, L. brevis Lbr-35, L. acidophilus La-14, B. lactis Bl-04, L. paracasei Lpc-37, and L. casei Lc-11.

Participants completed a daily survey that asked questions about daily nausea, vomiting frequency, constipation, and quality of life.

Participants reported that probiotic supplementation significantly reduced the severity of nausea, vomiting, and constipation. They also reported improvements in quality of life during probiotic supplementation. In addition, the researchers found that probiotic supplementation increased concentrations of free bile acids, which enhance GI motility and metabolism and improve GI function.

The study was conducted by researchers from the University of California, Davis. It was published online ahead of print on November 3, 2021 in the journal Nutrients.

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