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Resveratrol May Lower Production of Bad Cholesterol

High levels of LDL or “bad” cholesterol can lead to adverse cardiac events and are often treated with statins. However, taking a supplement of resveratrol may help lower LDL cholesterol in obese and overweight people by reducing the production of apolipoproteins B (ApoB).

ApoB is responsible for the transport of LDL cholesterol to tissues. High levels of ApoB appear to be related to heart disease.

Participants in the study included eight overweight or obese people who had slightly elevated triglyceride levels. The researchers examined them on two occasions that were four to six weeks apart.

Half of the group was instructed to take a resveratrol supplement while the other half took a placebo. For the first week, the resveratrol group took 1000 mg daily and for the second week they took 2000 mg daily.

At the conclusion of the study, the resveratrol group had no changes in insulin sensitivity or triglyceride levels but they did have lower levels of both ApoB48 (by 22%) and ApoB100 (by 27%).

The researchers noted that this was a small-scale study and more research should be conducted to determine the exact effects of resveratrol on cholesterol levels.

Researchers from the University of Toronto in Canada and Scuola Superiore Sant’Anna in Italy conducted the study. It was published online ahead of print on September 26, 2013, in the journal Arteriosclerosis, Thrombosis, and Vascular Biology.

Previous studies have shown resveratrol to be a powerful antioxidant with health benefits that include increasing energy levels, improving brain health, reducing the appearance of aging, lowering the risk of lung cancer, improving metabolism, regulating blood glucose levels in diabetics and improving liver function.

This antioxidant can be found in red wine, grapes, grape seed extract, and peanuts. A glass of red wine a day can provide a good amount of resveratrol, but excess drinking will reverse the positive health benefits. Another good way to get resveratrol is through a high quality supplement.

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