Study Finds Andrographis Paniculata Extract Helps Improve Knee Osteoarthritis Symptoms
osteoarthritis occurs when the cartilage in the knee joint gradually
wears away. Symptoms include stiffness, joint pain, and inflammation. A
new study suggests that Andrographis paniculata extract may help reduce pain and stiffness and improve function in people with mild to moderate knee osteoarthritis.
researchers recruited 103 participants with mild to moderate knee
osteoarthritis to participate in the study. The participants received
300 mg of Andrographis paniculata, 600 mg of Andrographis paniculata, or a placebo daily for eight weeks. The
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
was used to assess pain at baseline and at the end of the study. Joint
stiffness, physical function, and quality of life were also evaluated.
Participants who received the Andrographis paniculata
showed significant reductions in pain at days 28, 56, and 84 compared
to the placebo group. At the end of the study, both supplement groups
showed significant improvements in WOMAC stiffness scores, physical
function and quality of life compared to the placebo group.
The study was conducted by researchers from the University of Chile. It was published online ahead of print on April 10, 2019 in the journal Phytotherapy Research.