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Study Finds Mechanism Behind Resveratrol's Health Benefits

An abundant amount of research has been conducted in recent years linking resveratrol, the powerful antioxidant found in grapes and wine, to various health benefits. A new study conducted by researchers at the University of Texas has shed some light on the potential mechanism behind these benefits.

The study was published in the January 2010 issue of the Journal of Biological Chemistry.

The researchers found that resveratrol significantly enhanced the levels of DsbA-L in animal cells. DsbA-L is a protein that is known to regulate the expression of adiponectin. Recent research has found that DsbA-L levels tend to be considerably reduced in obese people, resulting in less availability of adiponectin.

Adiponectin is a fat hormone that plays an essential role in insulin sensitivity and energy production in our bodies. It has been associated with anti-obesity, anti-insulin resistance and anti-aging properties.

This was the first study to discover this new mechanism behind resveratrol’s health benefits and the researchers noted that these findings are particularly important for people who are obese and/or diabetic.

Resveratrol has gained an increasing amount of attention ever since researchers found that the powerful antioxidant is responsible for the “French Paradox.” The French paradox describes the low incidence of heart disease and obesity among the French, despite their relatively high-fat diet and levels of wine consumption.

Since then, further research has shown that resveratrol may also help with increasing energy levels, regulating blood glucose levels in diabetics, better brain health, lower risk of lung cancer, improving metabolism, and improved liver function.

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