Study Finds Resveratrol Helps Improve Bone Mineral Density in Postmenopausal Women

When women go through menopause, their levels of estrogen and other hormones drop sharply. Because estrogen helps maintain bone density, this drop can lead to significant bone loss and, over time, to low bone density. A new study suggests that resveratrol may help improve bone mineral density in postmenopausal women.

Participants in the study included 125 postmenopausal women with an average age of 65. They were given 150 mg of resveratrol or a placebo daily for 12 months. After 12 months, the participants switched interventions. The researchers used a Lunar Prodigy densitometer to assess participants’ bone mineral density and blood markers of bone metabolism at baseline and at the end of each intervention phase.

Resveratrol supplementation resulted in positive effects on bone mineral density in the lumbar spine and the neck of the femur. The increase in the femoral neck led to a reduction in the 10-year probability of major and hip fracture risk. Resveratrol supplementation also resulted in a 7.4% reduction in a bone resorption marker compared to placebo.

The study was conducted by researchers from the University of Newcastle. It was published online ahead of print on June 21, 2020 in theJournal of Bone and Mineral Research.