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Study Finds Supplement May Help Reduce "Mental Fatigue" During Exercise

Arginine silicate is a bioavailable source of arginine, silicon, and inositol. Previous research has suggested it may help increase blood flow and vasodilation. A new study has found that inositol-stabilized arginine silicate (ASI) may help improve cognitive function following intense exercise.

Twenty-four recreationally active males with an average age of 26.5 participated in the study. They were given 1500 mg of ASI or a placebo 30 minutes prior to a maximally graded exercise test. Cognitive function was evaluated before and after the exercise test via the Trail Making Test (TMT).

Participants in the ASI group saw statistically significant improvements in both parts of the TMT compared to the placebo group. Specifically, the time to complete the TMT Part A and B was reduced by 2.80 and 5.54 seconds respectively in the ASI group. In comparison, the placebo group saw increases of 19.82 and 7.68 seconds respectively.

The study was conducted by researchers from KGK Science. It was published on July 6, 2020 in the Journal of Exercise and Nutrition.

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