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Study Suggests Exercise May Overcome Genetics When it Comes to Obesity

Previous studies suggest that genetics may play a large role in people’s predisposition to obesity. Now a new study suggests that exercise may be able to overcome a genetic predisposition to obesity.


Participants in the study included 8,206 women who took part in the Women’s Health Initiative. The researchers used a linear regression model to examine the effects of 95 single-nucleotide polymorphisms BMI genetic risk score and physical activity on BMI. They used the data to determine if genetic associations are modified by physical activity and age.


The researchers found that exercise reduces the influence of genetic predisposition to obesity. They also found that the effect is more significant in women age 70 and older.


Researchers from University at Buffalo led the study. It was published on May 14, 2018, in the journal Menopause.


Regular exercise is one of the best things you can do for your health.  The Department of Health and Human Services recommends that adults aged 18-64 get at least two and a half hours (150 minutes) each week of moderate-intensity aerobic physical activity. Older adults should follow the adult guidelines as their abilities allow, and should do exercises that maintain or improve balance.

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