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ATP Supplement Associated With Weight Loss, Lower BMI

A recent study suggests that taking a supplement containing adenosine 5’-triphosphate (ATP) may help improve blood glucose and reduce waist circumference. The same study found that ATP taken in combination with glycine propionyl-L-carnitine hydrochloride may lower body weight and BMI.


The study included 67 participants, who were placed in one of four groups: 400 mg of ATP plus 2,000 mg of propionyl-L-carnitine hydrochloride; 400 mg of ATP; 2,000 mg of propionyl-L-carnitine hydrochloride; or a placebo. The intervention period lasted for 90 days. Blood sugar levels, body weight, BMI, waist and hip circumference, malondialdehdye levels, triglyceride levels and flow mediated dilation were measured at baseline, 30 days, 60 days, and 90 days.


At the conclusion of the study, the researchers found that the combination of ATP and propionyl-L-carnitine hydrochloride was associated with statistically significant decreases in body weight, BMI, waist and hip circumference, and waist/height ratio when compare to baseline. The ATP only group had significant decreases in blood glucose levels, waist and hip circumference, and waist/height ratio, when compared with baseline. They also had decreased levels of malondialdehyde, which is a marker of oxidative stress.


Finally, the propionyl-L-carnitine hydrochloride only group had statistically significant increases in flow mediated dilation and statistically significant decreases in MDA and triglyceride levels.


Researchers from Life Extension Clinical Research, Inc., conducted the study. It was published in the April 2017 issue of FASEB.


TP is the energy source for tissues. The human body recycles ATP continuously but usually only contains approximately 250 mg. Previous studies have linked ATP supplementation with health improvements in cases of kidney failure, high blood pressure, cystic fibrosis, lung cancer, and controlling blood pressure during surgery.


Because it is an energy source, ATP is abundant in a wide range of foods. If you’re looking to increase ATP in your diet, try adding more meat, fish, nuts, fruits and vegetables. If you want to make sure you’re getting the right amount, however, consider taking a high-quality supplement.


Propionyl-L-carnitine hydrochloride is an amino acid, which are the building blocks of proteins. Previous studies suggest that it may help with leg pain due to poor circulation, sexual performance problems in men, and low testosterone levels.

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