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Supplement Combination Found To Improve Joint Discomfort More Than Standard Supplement

Healthy joints are essential for maintaining mobility in the body and for being able to remain physically active. A recent study has found that supplementation with curcumagalactomannosides (a curcumin-fenugreek complex) and glucosamine hydrochloride may help improve joint pain, stiffness, and physical function more than supplementation with chondroitin sulfate and glucosamine hydrochloride.

Eighty adults diagnosed with osteoarthritis participated in the study. They were given a supplement containing 400 mg of curcumagalactomannosides and 500 mg of glucosamine hydrochloride or a supplement containing 415 mg of chondroitin sulfate and 500 mg of glucosamine hydrochloride daily for 84 days. Participants completed a treadmill uphill walking exercise and the researchers used the visual analogue scale score, Karnofsky Performance Scale score, and Western Ontario and McMaster Universities Osteoarthritis Index to evaluate joint pain, stiffness, and physical function at baseline, day 28, and day 84. Serum inflammation markers were also measured on the same days.

Participants in the curcumagalactomannosides- glucosamine hydrochloride group saw greater improvements in pain, stiffness, physical function, and walking performance than those in the chondroitin sulfate - glucosamine hydrochloride group. They also saw a significant reduction in serum inflammation markers compared to the chondroitin sulfate - glucosamine hydrochloride group. Overall, supplementation with curcumagalactomannosides - glucosamine hydrochloride was found to work approximately twice as well as supplementation with chondroitin sulfate - glucosamine hydrochloride.

The study was conducted by researchers from Aman Hospital and Research Center. It was published online ahead of print on July 14, 2020 in The Journal of Alternative and Complementary Medicine
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