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Supplementation With Anthocyanins May Help Improve Cardiometabolic Risk Factors in People With Metabolic Syndrome

Metabolic syndrome increases the risk of cardiovascular disease due to the cluster of metabolic conditions associated with it, including elevated blood pressure, impaired glucose tolerance, and elevated triglycerides and cholesterol. A recent study suggests that supplementation with anthocyanins from bilberries and blackcurrants may help improve some cardiometabolic risk factors.

Fifty-five people with an average age of 50 participated in the study. They were classified as normal/healthy or having metabolic syndrome. They were given 320 mg of anthocyanins twice daily for 4 weeks. Platelet coagulant activities, lipid profiles, fasting blood glucose, inflammatory markers, and oxidative stress markers were measured at baseline and at the end of the study.

Participants with metabolic syndrome saw a significant reduction in triglyceride and LDL-cholesterol levels. They also saw a 14% reduction in total cholesterol levels compared to baseline. Women with metabolic syndrome saw decreases in high sensitivity C-reactive protein, a marker of inflammation. In addition, participants with metabolic syndrome saw a 40% decrease in ADP-induced platelet activation.

No significant changes were seen in normal/healthy participants.

The study was conducted by researchers from Griffith University. It was published online ahead of print on February 27, 2020 in the journal Nutrition Research.

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