Supplementation With Curcuminoids and Piperine May Help Liver Health
Nonalcoholic fatty liver disease (NAFLD) is the build-up of extra fat in liver cells that is not caused by alcohol. Risk factors include obesity, gastric bypass surgery, high cholesterol, and type 2 diabetes. A recent study has found that supplementation with curcuminoids and piperine may help improve liver health in those with NAFLD.
Seventy people participated in the study. All had been diagnosed with NAFLD via an ultrasound. They took 500 mg of curcuminoids together with 5mg of piperine or a placebo daily for 12 weeks. The researchers measured NAFLD severity and liver function at the beginning and end of the study.
At the end of the study, NAFLD severity was significantly improved in the supplement group compared to the placebo group. Significant improvement was also seen in several liver function measurements, including serum concentrations of alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase.
The study was conducted by researchers from Baqiyatallah University of Medical Sciences. It was published online ahead of print on June 6, 2019 in theJournal of Cellular Biochemistry.