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Low Testosterone and Type-2 Diabetes May Increase Risk of Atherosclerosis

A recent study suggests that men who have low testosterone and Type-2 diabetes are at a greater risk of developing atherosclerosis than men who have diabetes but have normal testosterone levels. Atherosclerosis is a condition where plaque builds up in the arteries and inhibits blood flow.

Participants in the study included 115 men with Type 2 diabetes. They were all younger than 70 and had no history of heart disease. The researchers measured testosterone levels and atherosclerotic markers including intimal media thickening of the layers in the carotid artery, the presence of atherosclerotic plaques, function of the endothelial cells, and inflammatory markers.

They found that the men who had both low testosterone levels and Type 2 diabetes were six times more likely to have increased thickness of the carotid artery and endothelial dysfunction when compared with those who had normal testosterone levels. Fifty-four percent of the participants with low testosterone were found to be at higher risk for vascular disease, compared to only 10% of those with normal testosterone.

Researchers from the Hospital Universitario Sanatorio Guemes in Buenos Aires conducted the study. It was published online ahead of print on October 16, 2014 in The Journal of Clinical Endocrinology & Metabolism.

Atherosclerosis has been linked with blood clots and burst arteries as fats, cholesterol, and other harmful substances build up there. While maintaining a healthy diet and exercising regularly are the best ways to ward of atherosclerosis, previous studies suggest that supplements of CoQ10, aged garlic, and ashwagandha may all help as well.

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