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Supplements Can Raise Tocotrienols to Level Needed for Stroke Protection

Researchers previously believed that tocopherols (a form of vitamin E) prevent the absorption of tocotrienols (another form of vitamin E). A recent study however shows that oral supplementation with a blend of tocotrienols increases vitamin E levels in the tissues and organs, even when tocotrienols are present.

More notable was the finding that oral tocotrienol supplements (using Tocomin Suprabio®) raised the concentration of tocotrienols in blood to a level 20 times higher than the minimum amount previously shown to protect the brain from damage caused by a stroke.

The scientists noted this is the first study to show that oral tocotrienol supplements can raise tocotrienol levels throughout the body: in the blood, skin, brain, cardiac muscle, adipose and liver.

Conducted by researchers at the Ohio State University Medical Center, the findings of this study were published in the March, 2012 edition of the Journal of Nutrition.

Participants included 80 adults who represented a mix of healthy subjects and surgical patients. The surgical participants included individuals with heart failure, liver transplants, obese people who had received plastic surgery and epileptics.

The healthy participants all received 400 milligrams of tocotrienol daily for 12 weeks, while the surgery patients were assigned either 400 mg of tocotrienol or 400 mg of tocopherol for the same period of time. The researchers conducted skin biopsies and blood samples at the onset of the study and at the conclusion.

At the end of the 12 week period, the healthy participants showed noticeable increases in skin and blood levels of tocotrienols, as well as a 10-fold increase in tocotrienol levels in fat tissue compared to controls.

Vitamin E comes in eight different forms: four tocoperols (alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma, delta) and has been shown to help many aspects of the body. Tocopherol is the most common form in both the American diet and European diets, but tocotrienols are harder to obtain through dietary sources.

Previous studies have shown that vitamin E intake is associated with lower cholesterol, healthier skin, maintaining a proper hormonal balance, and preventing amyotrophic lateral sclerosis (ALS).

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