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Two Types of Vitamin E Taken Together May Boost Endothelial Function

Despite the fact that vitamin E is an effective antioxidant, attempts to use it to treat vascular disorders have been disappointing. A new study has found that a tocotrrienol/tocopherol complex may be the best combination of vitamin E to support endothelial function.


Endothelial function is a measure of how well the layer of cells that line the blood vessels function. Endothelial dysfunction typically leads to vascular disease if not treated.


The researchers tested the effects of single, pure tocotrienols (alpha, gamma, and delta), as well as alpha-tocopherol alone and a tocotrienol/tocopherol complex consisting of 78% tocotrienols and 22% alpha-tocopherol. They specifically looked at the effects of the different types of vitamin E on lowering oxidative stress and restoring endothelium-dependent relaxation in lab rats.


They found that the single, pure tocotrienols alone did effectively scavenge superoxide ions but did not improve endothelial function unless they were taken with alpha-tocopherol. Additionally, while alpha-tocopherol alone did restore endothelial function, the tocotrienol/tocopherol complex was more effective and required a lower dose to get the same results.


Researchers from the Royal Melbourne Institute of Technology University in Australia conducted the study. It was published online ahead of print on May 17, 2015, in Oxidative Medicine and Cellular Longevity.


The tocotrienol/tocopherol complex used in this study is called EVNol SupraBio™. Previous studies have shown that vitamin E intake is associated with lower cholesterol, healthier skin, maintaining a proper hormonal balance, and help reduce the risk of amyotrophic lateral sclerosis (ALS).


If you’re looking to add more vitamin E to your diet, try eating more sunflower seeds, breakfast cereal, tomatoes, dried herbs, and dried apricots.

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