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Type-II Collagen May Provide Pain Relief When Exercising

Some individuals with perfectly healthy joints still experience pain when working out. A recent study suggests that taking an undenatured type II collagen (UC-II) may improve joint pain in healthy people who only experience discomfort when exercising.


Participants in the study included adults who were physically active and only reported pain after exercising. Over the course of 180 days they were given either 40 mg of UC-II, 1500 mg glucosamine hydrochloride plus 1200 mg chondroitin sulfate, or a placebo.


The researchers pooled the data from two identically designed, randomized, double-blind, placebo-controlled studies focusing on people with osteoarthritis and found an overall reduction in WOMAC scores in the UC-II group compared to the placebo. There was also a reduction in the glucosamin/chondroitin group.


The WOMAC is the Western Ontario and McMaster Universities Osteoarthritis Index and is used to asses pain, stiffness, and physical function in people with hip and/or knee osteoarthritis.


The researchers also noted a significantly lower Lequesne Functional Index (LFI) and mean Visual Analog Scale (VAS) when compared with both the placebo group and the glucosamine-chondroitin group. The Lequesne Functional Index is a test used to test the severity of osteoarthritis of the knee joint.


Researchers from InterHealth conducted the study. It was presented at the 2015 Scripps Natural Supplement Conference: Natural Supplements: An Evidence-Based Update, which took place from January 16 - January 18, 2015 in San Diego, California. The researchers are currently preparing the manuscript for a peer-rated journal.

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