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Vitamin B5 Derivative May Lower Cholesterol

With 39.5% of Americans suffering from high LDL cholesterol (130 mg/dL or higher), it has become a serious problem in the US. Lifestyle changes, particularly in diet, are the best ways to control high cholesterol but sometimes a little extra help is needed. A recent study suggests that pantethine, a derivative of vitamin B5, may be a natural solution to this widespread problem.

The study was a joint effort between researchers from KGK Synergize, Kyowa Hakko USA and the Princeton Longevity Center. The findings were published in the August 2011 issue of Nutrition Research.

This was the first placebo-controlled and diet-controlled study of the effects of pantethine on high cholesterol and it included 120 North American participants who were at low to moderate risk for cardiovascular disease.

In order to start with a common base, all of the participants followed a therapeutic lifestyle change diet for one month. After that month, they were split into two groups, with one group receiving pantethine and one group receiving a placebo. The supplement group consumed 600 mg/d for 8 weeks and 900 mg/d for 8 more weeks.

At the conclusion of 16 weeks, the participants who maintained the therapeutic lifestyle change diet and consumed the pantethine supplements showed a reduction of 6 mg/dL (3%) in total cholesterol, 4 mg/dL (4%) in LDL (“bad”) cholesterol, and 4 mg/dL in apolipoprotein B. Apoliproprotein B is the main protein that binds to cholesterol and transports it throughout the circulatory system.

Vitamin B5 has also been linked to stress reduction, clearing acne, improving allergies, and hormone regulation. Some people even believe that it has the ability to slow the visible effects of aging, such as hair loss and wrinkles.

This vitamin can be found in many foods, including meats, eggs, milk, yeast, legumes, mushrooms, and whole wheat. If you think you're not getting enough vitamin B though diet alone, try a high quality daily supplement.

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