Vitamin D Supplementation Found to Improve Cardiovascular Risk Factors in Obese Children
Previous research has found that up to 49% of obese children may be vitamin D deficient. Now a new report has found that correcting vitamin D deficiency in obese children via supplementation may improve some cardiovascular risk factors including blood pressure, fasting glucose concentration, and insulin sensitivity.
Participants in the study included 225 children between the ages of 10 and 18 who were overweight or obese. They were given 600 IU of vitamin D, 1,000 IU, or 2,000 IU daily for six months. Arterial endothelial function, arterial stiffness, blood pressure, insulin sensitivity, and fasting glucose concentration were evaluated at baseline, three months, and six months.
Participants who received the 2,000 IU dose of vitamin D had a reduced fasting glucose concentration and improved insulin sensitivity following the supplementation period, compared to those who received the 600 IU dose. Participants who received the 1,000 or the 2,000 IU dose had lower blood pressure, compared to those who received the 600 IU dose. No changes were seen in arterial endothelial function or arterial stiffness.
The study was conducted by researchers from the University of Pittsburgh. It was published online ahead of print on January 17, 2020 in the American Journal of Clinical Nutrition.