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Weight Loss Due To Aging Associated With Worsening Bone Health

Many people lose weight as they age, but that weight loss may not be beneficial. A recent study suggests that weight loss may decrease bone density, architecture, and strength.


Participants in the study included 769 women and 595 men who were members of the Framingham Offspring Cohort and had a mean age of 70 years. All of the participants underwent high-resolution peripheral quantitative computed tomography (HR-pQCT) scanning at the tibia and radius from 2012 to 2016. The researchers took weight measurements every four to six years to assess recent weight change over six years and long-term change over 40 years.


At the conclusion of the study, the researchers noted that both short-term weight loss and long-term weigh loss contributed to micro-architectural deterioration of the bones, when compared with people who did not lose weight. They also found that people who lost 5% or more weight over 40 years were at a three-fold increased risk of fracture.


Researchers from Boston University School of Public Health conducted the study. It was published online ahead of print on May 29, 2018, in the Journal of Bone and Mineral Research.

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