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Support Healthy Free Testosterone and Nitric Oxide Levels
As men enter middle age, many start to feel the effects of andropause, which is associated with declining levels of free testosterone in the body. This typically affects libido, energy, stamina, strength and body composition.
Many supplements are promoted to help with these issues, but frankly very few ingredients have been subjected to clinical studies to assess efficacy and safety. The one ingredient that has been studied and found to work in multiple clinical trials is a patented extract of the herb tongkat ali branded as LJ100®.
LJ100® works in a number of ways, most notably by helping to normalize free testosterone levels (also known as “bioavailable” testosterone).
Although testosterone levels in men typically start to decline at age 40, the larger issue is much of it gets trapped and isn’t available to work in tissues. In fact, by age 60 it’s not uncommon that only about 2% of testosterone is free.
This is due to increasing levels or a hormone known as SHBG (sex hormone binding globulin) - which effectively takes testosterone out of circulation. LJ100® helps normalize SHBG levels which promotes an improvement in the free testosterone level.
Gynostemma helps boost nitric oxide levels in your arteries which helps promote blood flow. According to a Vanderbilt University study, gynostemma helps trigger the release of nitric oxide from artery walls - improving blood circulation.
Both maca (from Peru) and tribulus terrestris have been used traditionally to boost sexual health and energy.
LJ100®: 12 Clinical Studies Support Efficacy and Safety
Eurycoma longifolia is a medicinal plant found in South East Asia, It is commonly known as Tongkat Ali or Malaysian ginseng.
This plant has been used traditionally as an “anti-aging” remedy to help older individuals adapt to reduced energy, mood and libido that often comes with age.
LJ100® is the patented, proprietary, potent and original Tongkat Ali. LJ100® exemplifies “East meets West”- where human clinical trials and modern extraction method meets longstanding tradition.
LJ100® is standardized to 28% bioactive eurypeptides, 40% glycolsaponins and 1% eurycomanone - which represent the key nutritional compounds in Tongkat Ali root. Technologically sophisticated manufacturing methods ensure this ingredient is free from contamination - which can be a problem with other herbal products.
Originally developed by researchers at the University of Malaya and Massachusetts Institute of Technology (MIT), LJ100® has been shown in human clinical trials to help increase free testosterone and DHEA, and decrease sex hormone binding globulin (SHBG).
Healthy testosterone levels provide over 100 benefits to the body and are needed by men and women to maintain proper health.
Although testosterone levels in men typically start to decline at age 40, the larger issue is much of it gets trapped and isn’t available to work in tissues. In fact, by age 60 only about 2% of testosterone is free and readily available.
This is due to increasing levels of a hormone known as SHBG (sex hormone binding globulin) - which effectively takes testosterone out of circulation by binding to it.
LJ100® also increases cGMP and cAMP, which stimulate the relaxation phase on the smooth muscle that ultimately causes penile erection.
Further, LJ100® supports vitality by maintaining healthy IGF-1 levels, improving energy via accelerated production of adenosine triphosphate (ATP) and maintaining healthy androgen levels.
LJ100® Tongkat Ali has been used in 12 human clinical studies because it demonstrates efficacy while having an impressive safety profile.
LJ100® is classified under the World Health Organization, Global Harmony System, Classification of Chemicals, in Category 5, meaning no toxicity.
LJ100® is the only clinically studied Tongkat Ali extract for sexual functionality, sports nutrition and andropause.
The Finest Maca from Peru
Maca is believed to have been cultivated in the Junin plateau of Peru's Central Highlands as far back as 2,000 years ago for its aphrodisiac and fertility benefits.
The maca used in TrueMale™ is supplied by Naturex (a leading botanical ingredients company) and is branded as MacaPure™.
Naturex sources Maca in the central Peruvian Highlands, relying on partnerships with local growers. As a result of an extraordinarily well developed maca agriculture program, Naturex has access to the highest quality and most sustainably produced source of maca.
Participation in the Peruvian maca trade in this way enables Naturex to produce superior quality maca products, protects the natural Andean environment and enhances the future for some of the Andean people.
Two groups of novel compounds in maca have been identified by Naturex. These compounds are macamides and macaenes. These structures act as marker compounds for MacaPure™, ensuring its efficacy.
Preliminary experiments with animals point to these two groups of compounds as sex and energy enhancers. In the experiments, sexual activity and stamina increased significantly as the quantities of macamides and macaenes in the diet increased.
In addition, the MacaPure™ extract was tested for oral toxicity to ensure product safety. The end result was no toxicity and a complete absence of adverse pharmacological effects.
Dietary Supplement / 60 Vegetarian Capsules
Serving Size: 2 Capsules
Servings per Container: 30
|Amount Per Serving|
|LJ100® Tongkat Ali (Eurycoma longifolia) Root Extract (40% Glyco Saponins, 22% Eurypeptides)||100 mg*|
|Maca (Lepidium meyenii) Root Extract (0.6% macamides and macaenes)||500 mg*|
|Tribulus terrestris extract (fruit) (min. 60% total saponins, 20% protodioscin)||250 mg*|
|Gynostemma pentaphyllum extract (min. 95% gypenosides) (aerial parts)||80 mg*|
* Daily value not established.
Other ingredients: Hypromellose, rice flour, vegetable magnesium stearate and silica.
LJ100® is a registered trademark of HP Ingredients, Inc.
Suggested Use: Take two (2) capsules per day. For additional support take two (2) capsules twice (2) a day, at separate times of day. For maximum benefits, cycle this product five (5) days on and (2) days off, and eight (8) weeks on and two (2) weeks off.
TrueMALE™ helps support healthy free testosterone levels, promote sexual vigor and performance and boost energy metabolism and lean muscle gains.†
Keep out of reach of children.
Store at 15-30° C (59-86° F).
Protect from heat, light and moisture.
Do not purchase if seal is broken.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
- Gluten Free
- BPA Free
- Assembled in the USA
Manufactured for and Distributed by: NatureCity®
Boca Raton, FL 33487 www.naturecity.com
To re-order call toll free 1-800-593-2563
LJ 100 Tongkat Ali (Eurycoma Longifolia)
George A, Henkel R. “Phytoandrogenic properties of Eurycoma longifolia as natural alternative to testosterone replacement therapy.” Andrologia 2014 Sep;46(7):708-21.
Henkel RR, Wang R, Bassett SH, Chen T, Liu N, Zhu Y, Tambi MI. “Tongkat Ali as a potential herbal supplement for physically active male and female seniors--a pilot study.” Phytotherapy Research. 2014 Apr;28(4):544-50.
Udani J, Gruenwald J, Miller M, George A, Mufiza M, Abas A .“Effects of LJ100 on Sexual Performance & Well-being in Men with Reduced Sexual Potency”, Evidence-Based Complementary and Alternative Medicine, Volume 2014, Article ID: 179529.
Talbott SM, Talbott JA, George A, Pugh M. “Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects.” Journal of the International Society of Sports Nutrition. 2013 May 26;10(1):28.
Bahari Ismail S,WanMohammad W, George A, Hazlina Nik, Hussain N, Kamal Z, Liske E. “Randomized Clinical Trial on the Use of LJ100 for the Improvement of Quality of Life and Sexual Well-Being in Men.” Evidence-Based Complementary and Alternative Medicine, Volume 2012.
Tambi MI, Imran MK, Henkel RR. “Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism.” Andrologia. 2012 May;44 Suppl 1:226-30.
Tambi MI, Imran MK. “Eurycoma longifolia Jack in managing idiopathic male infertility.” Asian Journal of Andrology. 2010 May;12(3):376-80.
Sarina, M.Y. “Effects of Strength Training and LJ100 Supplementation on Strength and Muscle Size in Middle-aged Women.” 4th Asia-Pacific Conference on Exercise and Sport Science & 8th International Sports Science Conference (2009).
Talbott S, Christopulos A, Ekberg C. “Effect of a 6-week Lifestyle Program on Mood State and Metabolic Parameters in Moderately Overweight Subjects” Unpublished (2007).
Talbott S, Talbott J, Negrete J, Jones M, Nichols M, Roza J. “Effect of LJ100 on Anabolic Balance During Endurance Exercise.” Journal of International Society of Sport Medicine 3 (1): S32 2006.
Tambi, M.I. Kadir, A.B. “LJ100, a Potent Adaptogen, Maintains Healthy Aging in Men.” International Journal of Andrology, (2005). Vol. 28(Suppl 1):25-44.
S. Hamzah, A. Yusof. “The Ergogenic Effects Of Eurycoma Longifolia Jack: A Pilot Study.” British Journal of Sports Medicine. 2003;37:464-470.
Tambi, M.I., Othman S, Saad J.M. “LJ100® as a Potential Natural Energizer for Healthy Aging in Men.” First Asian Andrology Forum, Shanghai China 2002.
Other Tonghat Ali:
Chen C. K., Mohamad W. M. Z. W., Ooi F. K., Ismail S. B., Abdullah M, George A. “Supplementation of Eurycoma longifolia Jack Extract for 6 Weeks Does Not Affect Urinary Testosterone: Epitestosterone Ratio, Liver and Renal Functions in Male Recreational Athletes.” International Journal of Preventive Medicine. 2014 Jun; 5(6): 728–733.
Ulbricht C, Conquer J, Flanagan K, Isaac R, Rusie E, Windsor RC. “An evidence-based systematic review of tongkat ali (Eurycoma longifolia) by the Natural Standard Research Collaboration.” Journal of Dietary Supplements. 2013 Mar;10(1):54-83.
Bhat R, Karim AA. “Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance.” Fitoterapia. 2010 Oct;81(7):669-79.
Maca (Lepidium meyenii)
Gonzales GF, Villaorduña L, Gasco M, Rubio J, Gonzales C. “[Maca (Lepidium meyenii Walp), a review of its biological properties].” Rev Peru Med Exp Salud Publica. 2014;31(1):100-10.
Shin BC, Lee MS, Yang EJ, Lim HS, Ernst E. “Maca (L. meyenii) for improving sexual function: a systematic review.” BMC Complementary and Alternative Medicine. 2010 Aug 6;10:44.
Stone M, Ibarra A, Roller M, Zangara A, Stevenson E. “A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen.” Journal of Ethnopharmacology. 2009 Dec 10;126(3):574-6.
Gonzales GF, Gonzales C, Gonzales-Castañeda C. “Lepidium meyenii (Maca): a plant from the highlands of Peru--from tradition to science.” Forsch Komplementmed. 2009 Dec;16(6):373-80.
Gonzales GF, Gasco M, Lozada-Requena I. “Role of maca (Lepidium meyenii) consumption on serum interleukin-6 levels and health status in populations living in the Peruvian Central Andes over 4000 m of altitude.” Plant Foods for Human Nutrition. 2009 Apr;41(2):95-9.
Zenico T, Cicero AF, Valmorri L, Mercuriali M, Bercovich E. “Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: a randomised, double-blind clinical trial.” Andrologia. 2009 Apr;41(2):95-9.
Brooks NA, Wilcox G, Walker KZ, Ashton JF, Cox MB, Stojanovska L. “Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content.” Menopause. 2008 Nov-Dec;15(6):1157-62.
Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, Mischoulon D. “A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction.” CNS Neuroscience & Therapeutics. 2008 Fall;14(3):182-91.
Gonzales GF, Córdova A, Vega K, Chung A, Villena A, Góñez C, Castillo S. “Effect of Lepidium meyenii (Maca) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men.” Andrologia. 2002 Dec;34(6):367-72.
Gonzales GF, Cordova A, Gonzales C, Chung A, Vega K, Villena A. “Lepidium meyenii (Maca) improved semen parameters in adult men.” Asian Journal of Andrology. 2001 Dec;3(4):301-3.
Tribulus terrestris extract
Akhtari E, Raisi F, Keshavarz M, Hosseini H, Sohrabvand F, Bioos S, Kamalinejad M, Ghobadi A. “Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study.” Daru. 2014 Apr 28;22:40.
Sellandi TM, Thakar AB, Baghel MS. “Clinical study of Tribulus terrestris Linn. in Oligozoospermia: A double blind study.” Ayu. 2012 Jul;33(3):356-64.
Murthy AR, Dubey SD, Tripathi K. “Anti-hypertensive effect of Gokshura (Tribulus terrestris Linn.) - A clinical study.” Ancient Science of Life. 2000 Jan;19(3-4):139-45.
Park SH, Huh TL, Kim SY, Oh MR, Tirupathi Pichiah PB, Chae SW, Cha YS. “Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial.” Obesity (Silver Spring). 2014 Jan;22(1):63-71.
Huyen V, Phan D, Thang P, Ky P, Hoa N, Ostenson C. “Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients.” vol. 2012, Article ID 452313, 7 pages, 2012.
Amagase H, Campbell JH. Kinetic “Analysis of a Single Bolus Intake of Gynostemma pentaphyllum (Jiaogulan)-containing Liquid Dietary Supplement, JULE of the OrientTM on Human Peripheral Blood Circulation.” FASEB J. 2010; 24:lb334.
Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. “Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients.” Hormone and Metabolic Research. 2010 May;42(5):353-7.
Chou SC, Chen KW, Hwang JS, Lu WT, Chu YY, Lin JD, Chang HJ, See LC. “The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease.” Alternative Therapies In Health And Medicine. 2006 May-Jun;12(3):34-9.
Aktan F, Henness S, Roufogalis BD, Ammit AJ. “Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression.” Nitric Oxide 2003 Jun;8(4):235-42.
Tanner MA, Bu X, Steimle JA, Myers PR. “The direct release of nitric oxide by gypenosides derived from the herb Gynostemma pentaphyllum.” Nitric Oxide 1999 Oct;3(5):359-65.
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