- Supplements Facts
- Scientific References
- Client Reviews
The Remarkable Red Wine Polyphenol…
Resveratrol is a polyphenol found in small quantities in foods such as grapes, peanuts and some berries.
It has been suggested that resveratrol helps explain the “French Paradox.”, which wonders why the French have lower rates of heart disease despite a diet rich in saturated fat. Consumption of moderate amounts of red wine (and resveratrol) may be a contributing factor explaining this phenomenon.
Further, research by Harvard Medical School, the National Institute on Aging and others has shown that animals seem to live longer and better when supplementing their diets with resveratrol (this has not yet been demonstrated in humans).
The resveratrol in TrueResveratrol™ is trans-resveratrol. In case you are aren’t aware, there are two forms of resveratrol found naturally in plants such as Japanese knotweed and grapes. These are trans-resveratrol and CIS-resveratrol. Only trans-resveratrol has been shown to provide any significant health benefits.
Also important is the purity of the resveratrol in your product. In TrueResveratrolT, we use a powder that is 99% pure trans-resveratrol. If a product is only, for example, 50% pure resveratrol, this means the other 50% contains impurities (such as emodin) that can cause stomach discomfort. That’s not a problem with TrueResveratrolT.
Finally, even though resveratrol has become synonymous with red wine, the truth is grapes (and red wine) contain very low concentrations of resveratrol. That’s why nearly all resveratrol powder in supplements originates from the Japanese knotweed root - which naturally has a high concentration of resveratrol. From a supplement perspective, there’s no difference between resveratrol from grapes compared to Japanese knotweed.
Sometimes products are advertised as containing resveratrol from red wine grapes - and when you look at the details, typically the amount of resveratrol in the product is extremely low, or the grape powder is fortified with resveratrol from Japanese knotweed. In our view it does not make sense to pay a premium for these misleading products.
Dietary Supplement / 30 capsules
Serving Size: 1 Capsule
Servings per Container: 30
|Amount Per Serving|
|Trans-Resveratrol (99% Pure)||50 mg*|
* Daily Value not established.
Other ingredients: dicalcium phosphate, gelatin, cellulose, magnesium stearate and silica.
Suggested Use: Take one (1) to two (2) capsules daily with meals.
TrueResveratrol™ is made with 99% pure trans-resveratrol. This makes it virtually free of impurities and other unwanted compounds.
TrueResveratrol™ helps promote heart health while providing other antioxidant benefits.†
Keep out of reach of children.
Store at 15-30° C (59-86° F).
Protect from heat, light and moisture.
Do not purchase if seal is broken.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
- Assembled in the USA
Manufactured for and Distributed by: NatureCity®
Boca Raton, FL 33487 www.naturecity.com
To re-order call toll free 1-800-593-2563
Faghihzadeh F, Adibi P, Hekmatdoost A. “The effects of resveratrol supplementation on cardiovascular risk factors in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.” Britsh Journal of Nutrition. 2015 Sep 14;114(5):796-803.
Samsami-Kor M, Daryani NE, Asl PR, Hekmatdoost A. “Anti-Inflammatory Effects of Resveratrol in Patients with Ulcerative Colitis: A Randomized, Double-Blind, Placebo-controlled Pilot Study.”Archives of Medical Research. 2015 May;46(4):280-5.
Chen S, Zhao X, Ran L, Wan J, Wang X, Qin Y, Shu F, Gao Y, Yuan L, Zhang Q, Mi M. “Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.” Digestive and Liver Disease 2015 Mar;47(3):226-32.
Ornstrup MJ, Harsløf T, Kjær TN, Langdahl BL, Pedersen SB. “Resveratrol increases bone mineral density and bone alkaline phosphatase in obese men: a randomized placebo-controlled trial.” The Journal of Clinical Endocrinology & Metabolism. 2014 Dec;99(12):4720-9.
Witte AV, Kerti L, Margulies DS, Flöel A. “Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.” The Journal of Neuroscience. 2014 Jun 4;34(23):7862-70.
Liu K, Zhou R, Wang B, Mi MT. “Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials.” The American Journal of Clinical Nutrition. 2014 Jun;99(6):1510-9.
Dash S, Xiao C, Morgantini C, Szeto L, Lewis GF. “High-dose resveratrol treatment for 2 weeks inhibits intestinal and hepatic lipoprotein production in overweight/obese men.” Arteriosclerosis, Thrombosis, and Vascular Biology. 2013 Dec;33(12):2895-901.
Bo S, Ciccone G, Castiglione A, Gambino R, De Michieli F, Villois P, Durazzo M, Cavallo-Perin P, Cassader M. “Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial.” Current Medicinal Chemistry. 2013;20(10):1323-31.
Movahed A, Nabipour I, Lieben Louis X, Thandapilly SJ, Yu L, Kalantarhormozi M, Rekabpour SJ, Netticadan T. “Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients.” Evidence-Based Complementary and Alternative Medicine. Volume 2013 (2013, Sept), Article ID 851267, 11 pages.
Crandall JP, Oram V, Trandafirescu G, Reid M, Kishore P, Hawkins M, Cohen HW, Barzilai N. “Pilot study of resveratrol in older adults with impaired glucose tolerance.” Journals of Gerontology. Series A: Biological Sciences and Medical Sciences. 2012 Dec;67(12):1307-12.
Bhatt JK, Thomas S, Nanjan MJ. “Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus.” Nutrition Research. 2012 Jul;32(7):537-41.
Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P. “Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.” Cell Metabolism. 2011 Nov 2;14(5):612-22.
Brasnyó P, Molnár GA, Mohás M, Markó L, Laczy B, Cseh J, Mikolás E, Szijártó IA, Mérei A, Halmai R, Mészáros LG, Sümegi B, Wittmann I. “Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.” British Journal of Nutrition. 2011 Aug;106(3):383-9.
Ghanim H, Sia CL, Korzeniewski K, Lohano T, Abuaysheh S, Marumganti A, Chaudhuri A, Dandona P. “A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal.” Journal of Clinical Endocrinology and Metabolism. 2011 May;96(5):1409-14.
Kennedy DO, Wightman EL, Reay JL, Lietz G, Okello EJ, Wilde A, Haskell CF. “Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation.” American Journal of Clinical Nutrition. 2010 Jun;91(6):1590-7.
Brüll V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Müller C, Langguth P, Alteheld B, Fimmers R, Naaf S, Zimmermann BF, Stehle P, Egert S. “Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial.” Britsh Journal of Nutrition. 2015 Oct 28;114(8):1263-77.
Dower JI, Geleijnse JM, Gijsbers L, Schalkwijk C, Kromhout D, Hollman PC. “Supplementation of the Pure Flavonoids Epicatechin and Quercetin Affects Some Biomarkers of Endothelial Dysfunction and Inflammation in (Pre)Hypertensive Adults: A Randomized Double-Blind, Placebo-Controlled, Crossover Trial.” Journal of Nutrition. 2015 Jul;145(7):1459-63.
Perez A, Gonzalez-Manzano S, Jimenez R, Perez-Abud R, Haro JM, Osuna A, Santos-Buelga C, Duarte J, Perez-Vizcaino F. “The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity.” Pharmacological Research. 2014 Nov;89:11-8.
Boots AW, Drent M, de Boer VC, Bast A, Haenen GR. “Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis.” Clinical Nutrition. 2011 Aug;30(4):506-12.
Lee KH, Park E, Lee HJ, Kim MO, Cha YJ, Kim JM, Lee H, Shin MJ. “Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers.” Nutrition Research and Practice. 2011 Feb;5(1):28-33.
Heinz SA, Henson DA, Austin MD, Jin F, Nieman DC. “Quercetin supplementation and upper respiratory tract infection: A randomized community clinical trial.” Pharmacological Research. 2010 Sep;62(3):237-42.
Egert S, Bosy-Westphal A, Seiberl J, Kürbitz C, Settler U, Plachta-Danielzik S, Wagner AE, Frank J, Schrezenmeir J, Rimbach G, Wolffram S, Müller MJ. “Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study.” British Journal of Nutrition. 2009 Oct;102(7):1065-74.
Nieman DC, Henson DA, Gross SJ, Jenkins DP, Davis JM, Murphy EA, Carmichael MD, Dumke CL, Utter AC, McAnulty SR, McAnulty LS, Mayer EP. “Quercetin reduces illness but not immune perturbations after intensive exercise.” Medicine & Science in Sports & Exercise. 2007 Sep;39(9):1561-9.
*The views and opinions expressed by contributors and or product reviews are their own and not
necessarily those of NatureCity. These reviews should not be taken as recommendations but rather
client opinions of the products that they have used.