Aloe Vera and Inflammation
Modern science now understands how Aloe
vera attacks pain causing inflammation…
Aloe vera helps relieve your worst joint pains is by reducing inflammation. Scientific studies from clinics around the around the world have identified the many ways Aloe vera clobbers pain causing inflammation. For example…
#1. Aloe vera “Shoots” A Messenger of Pain Called Bradykinin
Bradykinin is part of the body’s complex mechanism that causes painful inflammation. In studies, Aloe vera has been shown to possess anti-bradykinin activity. Aloe vera contains the enzyme bradykinase, which breaks down bradykinin (1)(2). In this regard, Aloe vera can help knee pain, backpain, shoulder pain or other joint pain.
#2. Aloe vera Contains Plant Sterols That Are Powerful
Plant sterols, like steroid drugs, have an anti-inflammatory effect. However, steroids inhibit “healing” or tissue regeneration- which conversely Aloe vera promotes. Dr. Robert Davis found the natural sterols having the strongest anti inflammatory effect in Aloe vera are- lupeol, beta sitosterol, and campesterol. (3) (4)
#3. Aloe vera Contains an Aspirin Like Substance Called Salicylic Acid
Salicylic acid has pain relieving properties and reduces inflammation by inhibiting the production of prostaglandin hormones- which encourage inflammation. Aspirin or “acetylsalicylic acid” is chemically derived from natural salicylic acid. And we know, unlike aspirin, Aloe vera does not hurt your stomach or digestion- actually it helps it. Aloe vera may help knee pain, shoulder pain, back pain or other joint pain.
#4. Aloe vera Has a COX-2 Inhibiting Effect
Researchers in Mexico found that Aloe vera inhibits cyclooxygenase (COX-2), an enzyme that causes inflammation via the arachidonic acid pathway. Again, it does this without causing the unwanted side-effects of the COX-2 drugs.(5). Again, this may help your knee pain, back pain, shoulder pain or other joint pain.
#5. Aloe vera “Fixes” Digestion and Bowel Function- Overlooked
Causes of “Silent Inflammation”
Impaired digestion and poor absorption of proteins creates “foreign” invaders that your body views as a threat and seeks “protection” through inflammation. This “auto-immune” response ultimately results in conditions such as Rheumatoid arthritis, Irritable Bowel Syndrome (IBS), Crohn's disease and Colitis.
A study by Dr. Jeffrey Bland(6) showed how taking Aloe Vera internally improves protein digestion/absorption, balances acid levels, improves colonic activity and lowers bowel putrefaction- in just one week. By improving digestion and elimination, you help reduce chronic inflammation, potentially improving knee pain, back pain, shoulder pain and other joint pain.
#6. Aloe Polysaccharides Stimulate Fibroblasts
Which Grow and Repair Tissue
The “miracle” of Aloe is that it uniquely can reduce inflammation and promote tissue regeneration- which by itself helps reduce inflammation. Dr. Davis and Dr. Ivan Danhoff have shown that Aloe polysaccharides (long chain sugar molecules) stimulate fibroblasts that promote the tissue regrowth. But to do this, the polysaccharides need to be in the presence of the other Aloe nutrients- another reason why you want whole leaf aloe vera.
The polysaccharides also help the immune system remove toxic waste which has an anti-inflammatory benefit.
- "Bradykinase Activity in Aloe Extract: Fujita, K., Teradaira, R. & Nagatsu, T., BiochemicalPharmacology 25 205, 1976.
- Bautista-Perez R, Segura-Cobos D, Vasquez-Cruz B. In vitro antibradykinin activity of Aloe barbadensis gel. J Ethnopharmacol. July 2004;93(1):89-92.
- Davis R, Donato S, et al. Anti-inflammatory and wound healing activity of a growth substance in aloe vera. J Am Podiatr Med Assoc. 1994;84(2):77-81.
- Davis, RH: Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation. J of Am Podiatric Medical Assoc, 84(12), December, 1994, pp 614-619.
- Vazquez B, Avila G, et al. Anti-inflammatory activity of extracts from Aloe vera gel. J Ethnopharmacol. 1996;55(1):69-75.
- Bland, Jeffrey, “Effect of orally consumed Aloe Vera juice on gastrointestinal function in normal humans”. Preventative Medicine March/April, 1985