Hair thinning and excess shedding are common concerns — but can targeted nutrition help?
In this episode of the NatureCity Podcast, Carl Pradelli breaks down a new placebo-controlled study evaluating plant-based biotin (RGen-Bio®) and silica (RGgen-Si™), and their impact on hair loss, hair growth, thickness, and overall appearance. Plus, you’ll see how these nutrients helped skin and nails too.
You’ll learn how these nutrients support the hair growth cycle, why mitochondrial activity matters at the follicle level, and what the research actually showed after 90 days.
Watch now to see what the science says. → Learn more about TrueNuGrow+ at https://www.naturecity.com/products/truenugrow
WHAT YOU'LL LEARN IN THIS EPISODE
✓ How a 90-day placebo-controlled trial measured real improvements in hair loss, thickness, density, and shedding
✓ The three phases of hair growth and what causes follicles to shift into the shedding phase
✓ The role of biotin in keratin production and follicle metabolism
✓ How silica supports collagen formation to anchor hair follicles and strengthen the hair shaft
✓ Bonus benefits: skin elasticity, hydration, wrinkle reduction, and smoother nails from the same nutrients
EPISODE BREAKDOWN
A newly published randomized, double-blind, placebo-controlled study tested plant-based biotin (from RGen-Bio, extracted from the sesbania plant) and silica (from RGen-Si, extracted from bamboo shoots) on 97 men and women aged 20 to 60. All participants reported hair appearance concerns at baseline.
Over 90 days, participants taking 2.5 mg of biotin daily — or the biotin combined with 40mg of silica — experienced significant reductions in daily hair fall (normal hair loss), meaningful increases in hair thickness and density measured by advanced scalp imaging, and faster hair growth rates compared to placebo.
Carl explains how these results connect to the three-phase hair growth cycle: anagen (active growth), catagen (transition), and telogen (resting and shedding). When nutritional deficiencies, stress, or aging push more follicles into the telogen phase, shedding accelerates. Biotin supports keratin production and cellular energy metabolism in follicles, while silica supports the collagen and connective tissue that anchor hair in the scalp.
Researchers also observed improvements in skin elasticity, hydration, crow’s feet wrinkle appearance, and fingernail smoothness — because hair, skin, and nails share the same structural proteins and may all benefit from biotin and silica support.
NatureCity’s TrueNuGrow+ formula uses these exact plant-based biotin and silica sources at the same doses proven effective in this study, plus additional research-backed nutrients for comprehensive hair and skin support.
TIMESTAMPS
0:00 — Introduction and episode overview
0:31 — Why nutrition matters for hair health
1:32 — The new clinical study: design and participants
3:05 — Key results: less shedding, thicker and denser hair
4:52 — Understanding the hair growth cycle
6:15 — How biotin supports hair at the cellular level
7:14 — How silica strengthens hair structure
7:52 — Why the combination works
8:23 — Skin, nail, and anti-aging benefits
8:58 — TrueNuGrow+ formula and the study connection
9:11 — Final thoughts and where to learn more
