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A Pro-Inflammatory Diet May Be Associated With Increased Risk of Frailty

Foods with a high pro-inflammatory potential include red meat, processed meat, organ meat, refined carbohydrates such as white bread, white rice, and many desserts, and sweetened beverages. A recent study suggests that a pro-inflammatory diet may increase the risk of frailty in mature adults.

Participants in the study included 1,701 with an average age of 58 at the beginning of the study. Food frequency questionnaires were used to assess diet, and a dietary inflammatory index (DIE) score was assigned to each participant. Participants were followed for an average of 12 years and frailty was evaluated at the end of the study period.

Participants who had the highest DIE scores were more than twice as likely to develop frailty as those with the lowest DIE scores. The researchers found that a one-point higher DIE score (on a 16-point scale) was associated with a 16% higher risk of developing frailty.

The study was conducted by researchers from Harvard Medical School. It was published online ahead of print on September 24, 2021 in The American Journal of Clinical Nutrition.

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