Annurca Apple Extract May Increase Cholesterol Excretion
High cholesterol is a risk factor for heart disease. A recent study suggests that polyphenol extracts from Italian Annurca apples may increase cholesterol excretion by 35% in healthy people.
For the first part of this study, the researchers used an in vitro system. They found that apple extract was associated with an 86% decreased cholesterol micellar solubility. For the second part of the study, 50 healthy men and women were given a high-cholesterol diet with or without an Annurca apple-derived extract for 10 days. That was followed by a seven-day washout period, after which the participants crossed over to the other group.
The researchers found that cholesterol excretion in the feces increased by approximately 35% during the apple supplementation period, when compared with the placebo.
Researchers from the University of Naples Federico II in Italy led the study. It was published online ahead of print on May 17, 2018, in the journal PharmaNutrition.