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Equol and Resveratrol Associated with Reduction in Menopause Symptoms

Menopause brings about hormonal changes that can lead to a decrease in quality of life, ranging from change in sex drive to trouble sleeping. A recent study suggests that taking a supplement that contains equol and resveratrol may improve quality of life measures in healthy post-menopausal women.


Participants in the study included 60 healthy post-menopausal women who were given either a supplement containing 200 mg fermented soy containing 10 mg equol and 25 mg of resveratrol or a placebo daily for 12 weeks. The Menopause Rating Scale (MRS) was used to evaluate the severity of menopause-related complaints. The researchers also used the Hamilton Rating Scale for Depression (HAM-D) and the Nottingham Health Profile (NHP) to evaluate quality of life and sleep quality.


According to the MRS scores, 93% of both groups reported vaginal dryness at the beginning of the study.. By the conclusion of the study, only 13% of supplement group still reported vaginal dryness, compared with 90% in the placebo group. The supplement group also saw heart discomfort decrease from 63% to13% and a decrease in sexual problems from 100% to 27%.


The supplement group also saw reductions in anxiety and loss of interest in activity, as well as improvements in sleep quality.


Researchers from the University of Molise in Italy conducted the study. It was published in the February 2017 issue of Maturitas: The European Menopause Journal.


Equol is an isoflavandiol that previous studies suggest may help with bone health, skin health, and physiological changes during menopause. It is derived from soy foods.


Resveratrol is a powerful antioxidant with health benefits that include increasing energy levels, improving brain health, reducing the appearance of aging, improving metabolism, and improving liver function.


Resveratrol can be found in lower levels in a variety of foods including red wine, grapes, grape seed extract, and peanuts. A glass of red wine a day can provide a good amount of resveratrol, but excess drinking may counter balance the positive health benefits. Another good way to get resveratrol is through a high quality supplement.

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