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Lower Blood Pressure Linked to Reduced Risk of Mild Cognitive Impairment

Mild cognitive impairment (MCI) is a risk factor for the development of dementia. A new study has found that intensive control of blood pressure in mature adults may significantly reduce the risk of developing MCI.


9,361 participants in the Systolic Blood Pressure Intervention Trial Memory and Cognition in Decreased Hypertension trial were included in the study. All of the participants were over 50 and had hypertension, but did not have diabetes or history of stroke. They were assigned to either the standard treatment group, which had a blood pressure goal of less than 140 mm HG, or the intensive treatment group, which had a blood pressure goal of less than 120 mm HG.


After 5 years of blood pressure intervention the participants were classified as having no cognitive impairment, MCI, or possible dementia.


The researchers found that participants in the intensive treatment group had a significantly reduced risk of mild cognitive impairment. No significant reduction in dementia was seen in either group.


The study was conducted by researchers from the Wake Forest School of Medicine. It was published January 28, 2019 in the Journal of the American Medical Association.

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