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Probiotic Strain May Reduce Body Mass, Calorie Intake in Overweight Adults

A recent study suggests that consuming the probiotic Bifidobacterium animalis ssp. Lactis 420 (B420), either with or without a prebiotic fiber, may help reduce body fat mass, trunk fat mass, waist circumference, and calorie intake in overweight adults.


Participants in the study included 225 people between the ages of 18-65 with a BMI between 28 and 34.9 mg/m2. None of the participants had diabetes or cardiovascular disease. Additionally, people who had used fiber supplements or probiotics in the six weeks prior were excluded from the study.


Over the course of six months, the participants underwent one of four treatments:




    1. a placebo consisting of 12 g per day of microcrystalline cellulose per day;

    1. 12 g per day of the prebiotic fiber Litesse Ultra polydextrose

    1. 10 billion CFU of B420 per day;

    1. a combination of the prebiotic fiber and the probiotic.


At the conclusion of the study, the researchers noted that the probiotic group and the probiotic/prebiotic combo group lost approximately 3.1 more pounds than the placebo group. They also noted that the two groups showed reduced body fat mass, trunk fat mass, waist circumference, and calorie intake, when compared with the placebo.


Researchers from DuPont Nutrition & Health conducted the study. It was published online ahead of print on October 26, 2016, in EBioMedicine.


Previous studies suggest that Bifidobacterium animalis ssp. Lactis 420 may reduce the risk of body weight gain and diabetes, but studies specifically examining this probiotic are new. It occurs naturally in dairy products but for best results, seek out a high quality, tested supplement.

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