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Resveratrol May Help Improve Bone Health of Men With Metabolic Syndrome

Metabolic syndrome has been linked with low-grade inflammation that can lead to bone loss. A recent study suggests that taking a supplement of resveratrol may help improve spinal bone density in men with metabolic syndrome.


Metabolic syndrome is a group of risk factors associated with chronic disease, including high blood pressure, insulin resistance, large waist circumference, high triglyceride levels and high cholesterol. Those risk factors include high levels of triglycerides, abdominal obesity, high fasting blood sugar and high cholesterol.

Participants in the study included 66 middle-aged men with metabolic syndrome. They were given either 500 mg of resveratrol, 75 mg of resveratrol, or a placebo twice a day for 16 weeks.

At the conclusion of the study, the researchers found that the men who took the higher dose of resveratrol had a 2.6% increase in lumbar spine volumetric bone mineral density compared to the placebo group. They also had a 16% increase in levels of the bone formation marker bone alkaline phosphatase compared to the placebo group.

Researchers from the University Hospital in Aarhus, Denmark, conducted the study. It was published online ahead of print on October 16, 2014, in the Journal of Clinical Endocrinology & Metabolism.

Previous studies have shown resveratrol to be a powerful antioxidant with health benefits that include increasing energy levels, improving brain health, reducing the appearance of aging, improving metabolism, and improving liver function.

This antioxidant can be found in red wine, grapes, grape seed extract, and peanuts. A glass of red wine a day can provide a good amount of resveratrol, but excess drinking may counter balance the positive health benefits. Another good way to get resveratrol is through a high quality supplement.

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